Salve!
AutorInnen
WiKu Reihen
Wirtschaft
Management
Internat. Forschung
Jura
Kriminologie
Pädagogik
Phil. & Psy.
Sprach-/Kulturw.
Medizin/Gesundheit
Melanom
Disease Management
Evidenzmedizin
Glukoseaufzeichnung
PTHrP-Hormone
Psychometrie
Rauschdrogen
Risiko-Index
Rosazea
Magersucht
Schizophrenie
BGM 2003
BGM 2004
BGM 2005
BGM 2006
Kinesin
Bovine IGF2
Tumorerkrankung
eLearning
Technik
Informatik
Naturwissenschaft
Belletristik
Informationen
BESTELLEN
Glücks-KLEE
Impressum
   
 




ISBN 3-86553-124-5: Claudia Maria Gebert, Characterization of gene expression an methylation patterns of the bovine IGF2 gene in gametes and preimplantion embryos of different origins 

192 Seiten, 42,65 Euro

In jeder guten Buchhandlung bestellbar, direkt beim Verlag oder hier bei Amazon:



DNA methylation at cytosine molecules is one of the best known epigenetic mechanisms to date and involved in genomic imprinting. Imprinting is characterized by mono-allelic gene expression and plays a crucial role during early mammalian development. While insight into the epigenetic phenomenon of imprinting is mainly derived from mice and humans, information is scarce in cattle.

This study reports the methylation status of the bovine Insulin-like growth factor2 gene (IGF2) in gametes and preimplantation embryos of different origins including cloned bovine embryos. Additionally, expression patterns of the bovine IGF2, Insulinlike growth factor2 receptor (IGF2R) and Mammalian achaete-scute homologue2 (Mash2) genes were characterized in bovine blastocysts. This is the first study of DNA methylation within the bovine IGF2 gene in preimplantation embryos and the first report about the identification of an intragenic Differentially Methylated Region (DMR) within a bovine imprinted gene.